These Publications are listed alphabetically by Author then Title.

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This database will be updated continually.

Publications by our Fellows

Barbie DA – AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer
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Barbie DA – Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
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Bass, Adam – SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
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Bastas G – Bioinformatic requirements for protein database searching using predicted epitopes from disease-associated antibodies.
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Battinelli E, Loscalzo J. – Nitric oxide induces apoptosis in megakaryocytic cell lines
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Battinelli E, Willoughby SR, Foxall T, Valeri CR, Loscalzo J – Induction of platelet formation from megakaryocytoid cells by nitric oxide.
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Battinelli EM – Reversal of new oral anticoagulants
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Battinelli EM, Ansell J. – Cancer and thrombosis
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Battinelli EM, Bauer KA – Thrombophilias in pregnancy
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Battinelli EM, Boyd Y, Craig IW, Breakefield XO, Chen ZY – Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp).
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Battinelli EM, Hartwig JH, Italiano JE Jr. – Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis
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Battinelli EM, Markens BA, Italiano JE Jr – Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis
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Battinelli EM, Murphy DL, Connors JM – Venous thromboembolism overview
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Bausch D – Colon carcinoma tumor immunology in the CT-26 mouse model: "immune escape" mechanisms
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Bausch, D – The angiogenic role of polymorphonuclear neutrophil derived matrix metalloproteinase-9 and its interaction with tumor derived VEGF
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Campbell, J – Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.
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Campbell, J – Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.
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Campbell, Joshua – Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations.
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Chen ZY, Battinelli EM, Fielder A, Bundey S, Sims K, Breakefield XO, Craig IW – A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy.
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Chen ZY, Battinelli EM, Hendriks RW, Powell JF, Middleton-Price H, Sims KB, Breakefield XO, Craig IW – Norrie disease gene: characterization of deletions and possible function
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Chen ZY, Battinelli EM, Woodruff G, Young I, Breakefield XO, Craig IW. – Characterization of a mutation within the NDP gene in a family with a manifesting female carrier.
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Chitalia VC – Jade-1 inhibits Wnt signaling by ubiquitinating live-catenin and mediates Wnt pathway inhibition by pVHL
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Cho NL – Estrogen receptor α or β loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFβ and HNF3β signaling
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Cho, NL – Immunohistochemical and molecular analysis of tyrosine kinase activity in desmoid tumors
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Cho, NL – Mesenchymal stromal cell mutations and wound healing contribute to the etiology of desmoid tumors
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Crasta, Karen – DNA Breaks and Chromosome Pulverization from Errors in Mitosis
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Dai, Y. – Determinants of HMGB Proteins Required To Promote RAG1/2-Recombination Signal Sequence Complex Assembly and Catalysis during V (D) J Recombination
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Dai, Y. – Non-homologous end joining and V (D) J recombination require an additional factor
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Dai, Y. – Prohibitin and the SWI/SNF ATPase Subunit BRG1 are Required for Androgen-antagonist-mediated Transcriptional
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Dai, Y. – SIRT1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor.
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Dai, Y. – Transcription Regulation by Class III Histone Deacetylases (HDACs) - Sirtuins.
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Dominguez, Isabel – CK2 and its role in Wnt and NF-kB signaling: Linking development and cancer
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Feng H – Heat-shock induction of T-cell lymphoma/leukaemia in conditional Cre/lox-regulated transgenic zebrafish
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Feng H – T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation
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Feng, Hui – BCL2-specific inhibitor ABT-199 synergizes strongly with cytarabine against the early immature LOUCY cell line but not more-differentiated T-ALL cell lines
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Flaumenhaft R, Dilks JR, Richardson J, Alden E, Patel-Hett SR, Battinelli E, Klement GL, Sola-Visner M, Italiano JE Jr. – Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles.
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Flynn R L, Richard C. Centore, Roderick J. O’Sullivan, Rekha Rai, Alice Tse, Zhou Songyang, Sandy Chang, Jan Karlseder, and Lee Zou – TERRA and hnRNPA1 Orchestrate an RPA-to-POT1 Switch on Telomeric Single-Stranded DNA
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Flynn, Rachel – Alternative Lengthening of Telomeres Renders Cancer Cells Hypersensitive to ATR Inhibitors
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Freedman JE, Sauter R, Battinelli EM, Ault K, Knowles C, Huang PL, Loscalzo J. – Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene.
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Ganem, Neil – A Mechanism Linking Extra Centrosomes to Chromosome Instability
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Ganem, Neil – Cytokinesis failure triggers Hippo pathway activation
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Gao, D., Inuzuka H., Korenjak M., Tseng A., Wu T., Wan L., Kirschner M., Dyson N. and Wei, W. – Cdh1 regulates cell cycle through modulating the Claspin/Chk1 and the Rb/E2F1 pathways.
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Gao, D., Inuzuka, H., Tseng, A., Chin, R., Toker, A. and Wei, W. (2009) – Phosphorylation by Akt1 promotes Skp2 cytoplasmic localization and impairs APC/Cdh1-medaited Skp2 destruction.
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Garcia-Marcos, Mikel – RESEARCH SUMMARY
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Gewurz, BE – B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus
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Gewurz, BE – Capravirine, a nonnucleoside reverse-transcriptase inhibitor in patients infected with HIV-1: a phase 1 study
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Gewurz, BE – DNA-damage control: Claspin destruction turns off the checkpoint
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Gewurz, BE – Either B7 costimulation or IL-2 can elicit generation of primary alloreactive CTL
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Gewurz, BE – Human babesiosis
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Gewurz, BE – Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner
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Gewurz, BE – Human herpesvirus 6 encephalitis
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Gewurz, BE – IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3
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Gewurz, BE – Localization of sequence-determined neoepitopes and neutrophil digestion fragments of C-reactive protein utilizing monoclonal antibodies and synthetic peptides.
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Gewurz, BE – Persistent and relapsing babesiosis in immunocompromised patients
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Gewurz, BE – Phenotypic switching of Haemophilus influenzae
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Gewurz, BE – Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6794-9.
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Gewurz, BE – Reactivity of anti-human C-reactive protein (CRP) and serum amyloid P component (SAP) monoclonal antibodies with limulin and pentraxins of other species
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Gewurz, BE – US2, a human cytomegalovirus-encoded type I membrane protein, contains a non-cleavable amino-terminal signal peptide.
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Gewurz, BE – Viral subversion of the immune system
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Gewurz, BE – Virus subversion of immunity: a structural perspective
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Italiano JE Jr, Battinelli EM – Selective sorting of alpha-granule proteins
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Lian CG – The management of antibody-mediated rejection in the first presensitized recipient of a full-face allotransplant.
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Lian, CG – Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury.
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Lian, CG – Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity.
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Lian, CG – Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors.
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Liss, Andrew – Activation of ERK and JNK pathways is essential for transformation by the v-rel oncogene
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Liss, Andrew – AP-1 factors play an important role in transformation induced by the v-Rel oncogene
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Liss, Andrew – Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kB oncogenesis
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Liss, Andrew – Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
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Liss, Andrew – Mechanism of telomerase activation by v-Rel and its contribution to transformation
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Liss, Andrew – Mutational analysis of the v-Rel dimerization interface reveals a critical role for v-Rel homodimers in transformation
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Liss, Andrew – Normalization of luciferase reporter assays under conditions that alter internal controls
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Liss, Andrew – Synergistic stimulation of avian I kappa B alpha transcription by rel and fos/jun factors
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Liss, Andrew – Targeted disruption of Mib2 causes exencephaly with a variable penetrance
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Liss, Andrew – The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation
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Liss, Andrew – The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB
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Liss, Andrew – The differential regulation of the inhibitor of apoptosis ch-IAP1 by v-rel and the proto-oncogene c-rel
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Liss, Andrew – The suppression of SH3BGRL is important for v-Rel-mediated transformation
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Mischoulon D, Rosenbaum J, editors – Natural medications for psychiatric disorders: considering the alternatives, 2nd ed.Philadelphia: Lippincott Williams & Wilkins, 2008
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Pavel AB – Alterations in Bronchial Airway miRNA Expression for Lung Cancer Detection.
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Perissi, V – A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2
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Sompuram SR – Accurate identification of paraprotein antigen targets by epitope reconstruction.
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Varelas, Xaralabos – Coordinating developmental signaling: novel roles for the Hippo pathway
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Varelas, Xaralabos – Integrating developmental signals: a Hippo in the (path) way
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Varelas, Xaralabos – Integrating developmental signals: a Hippo in the (path)way.
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Varelas, Xaralabos – TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
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Varelas, Xaralabos – The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGFlive/Smad Pathway
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Varelas, Xaralabos – The Hippo Pathway Regulates Wnt/live-Catenin Signaling
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Wilson, F. – MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells
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Wilson, Fred – A functional landscape of resistance to ALK inhibition in lung cancer
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Wu Hao – Threonine 393 of live-Catenin Regulates Interaction With Axin
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Wu, Muzhou – Emerging Biomarkers in Cutaneous Melanoma
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Wu, Muzhou – MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma.
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Wu, Muzhou – Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.
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Wu, Muzhou – Targeting the CoREST Complex with Dual Histone Deacetylase and Demethylase Inhibitors.
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Yaglom, Julia – HEAT SHOCK PROTEIN HSP72 CONTROLS ONCOGENE-INDUCED SENESCENCE PATHWAYS IN CANCER CELLS.
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Yaglom, Julia – Hsp72 regulates DNA damage signaling in cancer cells
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Yaglom, Julia – Triggering senescence programs suppresses Chk1 kinase and sensitizes cells to genotoxic stresses
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