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Publications by our Fellows

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

The management of antibody-mediated rejection in the first presensitized recipient of a full-face allotransplant.
Lian CG (more...)

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer
Barbie DA (more...)

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
Barbie DA (more...)

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
Bass, Adam (more...)

Bioinformatic requirements for protein database searching using predicted epitopes from disease-associated antibodies.
Bastas G (more...)

Nitric oxide induces apoptosis in megakaryocytic cell lines
Battinelli E, Loscalzo J. (more...)

Induction of platelet formation from megakaryocytoid cells by nitric oxide.
Battinelli E, Willoughby SR, Foxall T, Valeri CR, Loscalzo J (more...)

Reversal of new oral anticoagulants
Battinelli EM (more...)

Cancer and thrombosis
Battinelli EM, Ansell J. (more...)

Thrombophilias in pregnancy
Battinelli EM, Bauer KA (more...)

Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp).
Battinelli EM, Boyd Y, Craig IW, Breakefield XO, Chen ZY (more...)

Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis
Battinelli EM, Hartwig JH, Italiano JE Jr. (more...)

Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis
Battinelli EM, Markens BA, Italiano JE Jr (more...)

Venous thromboembolism overview
Battinelli EM, Murphy DL, Connors JM (more...)

Colon carcinoma tumor immunology in the CT-26 mouse model: "immune escape" mechanisms
Bausch D (more...)

The angiogenic role of polymorphonuclear neutrophil derived matrix metalloproteinase-9 and its interaction with tumor derived VEGF
Bausch, D (more...)

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.
Campbell, J (more...)

Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations.
Campbell, Joshua (more...)

A mutation in the Norrie disease gene (NDP) associated with X-linked familial exudative vitreoretinopathy.
Chen ZY, Battinelli EM, Fielder A, Bundey S, Sims K, Breakefield XO, Craig IW (more...)

Norrie disease gene: characterization of deletions and possible function
Chen ZY, Battinelli EM, Hendriks RW, Powell JF, Middleton-Price H, Sims KB, Breakefield XO, Craig IW (more...)

Characterization of a mutation within the NDP gene in a family with a manifesting female carrier.
Chen ZY, Battinelli EM, Woodruff G, Young I, Breakefield XO, Craig IW. (more...)

Jade-1 inhibits Wnt signaling by ubiquitinating live-catenin and mediates Wnt pathway inhibition by pVHL
Chitalia VC (more...)

Estrogen receptor α or β loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFβ and HNF3β signaling
Cho NL (more...)

Immunohistochemical and molecular analysis of tyrosine kinase activity in desmoid tumors
Cho, NL (more...)

Mesenchymal stromal cell mutations and wound healing contribute to the etiology of desmoid tumors
Cho, NL (more...)

DNA Breaks and Chromosome Pulverization from Errors in Mitosis
Crasta, Karen (more...)

Determinants of HMGB Proteins Required To Promote RAG1/2-Recombination Signal Sequence Complex Assembly and Catalysis during V (D) J Recombination
Dai, Y. (more...)

Non-homologous end joining and V (D) J recombination require an additional factor
Dai, Y. (more...)

Prohibitin and the SWI/SNF ATPase Subunit BRG1 are Required for Androgen-antagonist-mediated Transcriptional
Dai, Y. (more...)

SIRT1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor.
Dai, Y. (more...)

Transcription Regulation by Class III Histone Deacetylases (HDACs) - Sirtuins.
Dai, Y. (more...)

CK2 and its role in Wnt and NF-kB signaling: Linking development and cancer
Dominguez, Isabel (more...)

Heat-shock induction of T-cell lymphoma/leukaemia in conditional Cre/lox-regulated transgenic zebrafish
Feng H (more...)

T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation
Feng H (more...)

BCL2-specific inhibitor ABT-199 synergizes strongly with cytarabine against the early immature LOUCY cell line but not more-differentiated T-ALL cell lines
Feng, Hui (more...)

Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles.
Flaumenhaft R, Dilks JR, Richardson J, Alden E, Patel-Hett SR, Battinelli E, Klement GL, Sola-Visner M, Italiano JE Jr. (more...)

TERRA and hnRNPA1 Orchestrate an RPA-to-POT1 Switch on Telomeric Single-Stranded DNA
Flynn R L, Richard C. Centore, Roderick J. O’Sullivan, Rekha Rai, Alice Tse, Zhou Songyang, Sandy Chang, Jan Karlseder, and Lee Zou (more...)

Alternative Lengthening of Telomeres Renders Cancer Cells Hypersensitive to ATR Inhibitors
Flynn, Rachel (more...)

Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene.
Freedman JE, Sauter R, Battinelli EM, Ault K, Knowles C, Huang PL, Loscalzo J. (more...)

A Mechanism Linking Extra Centrosomes to Chromosome Instability
Ganem, Neil (more...)

Cytokinesis failure triggers Hippo pathway activation
Ganem, Neil (more...)

Cdh1 regulates cell cycle through modulating the Claspin/Chk1 and the Rb/E2F1 pathways.
Gao, D., Inuzuka H., Korenjak M., Tseng A., Wu T., Wan L., Kirschner M., Dyson N. and Wei, W. (more...)

Phosphorylation by Akt1 promotes Skp2 cytoplasmic localization and impairs APC/Cdh1-medaited Skp2 destruction.
Gao, D., Inuzuka, H., Tseng, A., Chin, R., Toker, A. and Wei, W. (2009) (more...)

Garcia-Marcos, Mikel (more...)

B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus
Gewurz, BE (more...)

Capravirine, a nonnucleoside reverse-transcriptase inhibitor in patients infected with HIV-1: a phase 1 study
Gewurz, BE (more...)

DNA-damage control: Claspin destruction turns off the checkpoint
Gewurz, BE (more...)

Either B7 costimulation or IL-2 can elicit generation of primary alloreactive CTL
Gewurz, BE (more...)

Human babesiosis
Gewurz, BE (more...)

Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner
Gewurz, BE (more...)

Human herpesvirus 6 encephalitis
Gewurz, BE (more...)

IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3
Gewurz, BE (more...)

Localization of sequence-determined neoepitopes and neutrophil digestion fragments of C-reactive protein utilizing monoclonal antibodies and synthetic peptides.
Gewurz, BE (more...)

Persistent and relapsing babesiosis in immunocompromised patients
Gewurz, BE (more...)

Phenotypic switching of Haemophilus influenzae
Gewurz, BE (more...)

Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6794-9.
Gewurz, BE (more...)

Reactivity of anti-human C-reactive protein (CRP) and serum amyloid P component (SAP) monoclonal antibodies with limulin and pentraxins of other species
Gewurz, BE (more...)

US2, a human cytomegalovirus-encoded type I membrane protein, contains a non-cleavable amino-terminal signal peptide.
Gewurz, BE (more...)

Viral subversion of the immune system
Gewurz, BE (more...)

Virus subversion of immunity: a structural perspective
Gewurz, BE (more...)

Selective sorting of alpha-granule proteins
Italiano JE Jr, Battinelli EM (more...)

Biomarker evaluation of face transplant rejection: association of donor T cells with target cell injury.
Lian, CG (more...)

Long-term dietary sodium restriction increases adiponectin expression and ameliorates the proinflammatory adipokine profile in obesity.
Lian, CG (more...)

Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors.
Lian, CG (more...)

Activation of ERK and JNK pathways is essential for transformation by the v-rel oncogene
Liss, Andrew (more...)

AP-1 factors play an important role in transformation induced by the v-Rel oncogene
Liss, Andrew (more...)

Cell transformation by v-Rel reveals distinct roles of AP-1 family members in Rel/NF-kB oncogenesis
Liss, Andrew (more...)

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
Liss, Andrew (more...)

Mechanism of telomerase activation by v-Rel and its contribution to transformation
Liss, Andrew (more...)

Mutational analysis of the v-Rel dimerization interface reveals a critical role for v-Rel homodimers in transformation
Liss, Andrew (more...)

Normalization of luciferase reporter assays under conditions that alter internal controls
Liss, Andrew (more...)

Synergistic stimulation of avian I kappa B alpha transcription by rel and fos/jun factors
Liss, Andrew (more...)

Targeted disruption of Mib2 causes exencephaly with a variable penetrance
Liss, Andrew (more...)

The activation of TC10, a Rho small GTPase, contributes to v-Rel-mediated transformation
Liss, Andrew (more...)

The chicken RelB transcription factor has transactivation sequences and a tissue-specific expression pattern that are distinct from mammalian RelB
Liss, Andrew (more...)

The differential regulation of the inhibitor of apoptosis ch-IAP1 by v-rel and the proto-oncogene c-rel
Liss, Andrew (more...)

The suppression of SH3BGRL is important for v-Rel-mediated transformation
Liss, Andrew (more...)

Natural medications for psychiatric disorders: considering the alternatives, 2nd ed.Philadelphia: Lippincott Williams & Wilkins, 2008
Mischoulon D, Rosenbaum J, editors (more...)

Alterations in Bronchial Airway miRNA Expression for Lung Cancer Detection.
Pavel AB (more...)

A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2
Perissi, V (more...)

Accurate identification of paraprotein antigen targets by epitope reconstruction.
Sompuram SR (more...)

Coordinating developmental signaling: novel roles for the Hippo pathway
Varelas, Xaralabos (more...)

Integrating developmental signals: a Hippo in the (path) way
Varelas, Xaralabos (more...)

Integrating developmental signals: a Hippo in the (path)way.
Varelas, Xaralabos (more...)

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
Varelas, Xaralabos (more...)

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGFlive/Smad Pathway
Varelas, Xaralabos (more...)

The Hippo Pathway Regulates Wnt/live-Catenin Signaling
Varelas, Xaralabos (more...)

A functional landscape of resistance to ALK inhibition in lung cancer
Wilson, Fred (more...)

Threonine 393 of live-Catenin Regulates Interaction With Axin
Wu Hao (more...)

Yaglom, Julia (more...)

Hsp72 regulates DNA damage signaling in cancer cells
Yaglom, Julia (more...)

Triggering senescence programs suppresses Chk1 kinase and sensitizes cells to genotoxic stresses
Yaglom, Julia (more...)